The Recent Advances in Crystallographic Fragment Screening Satellite Workshop will bring together research groups from all over the world who are active in the application and/or the development of crystallographic fragment screening.
The community includes scientists from large-scale facilities (synchrotrons), method developers as well as researchers from academia and industry. The goal of the workshop is to disseminate recent advances and applications related to crystallographic fragment screening.
This workshop will be complementary to a micro-symposium on fragment-screening within the IUCr-2023 congress.
Several IUCr Grants will be available for students and early career researchers (within 5 yrs of PhD) to cover part of travel and accommodation expenses. Please indicate during registration if you wish to be considered for an IUCr Grant.
RACFS Statements
Please review our gender balance, diversity statements and code of conduct.
Download RACFS StatementsRegistration
Registration for the event is now open.
Several IUCr Grants will be available for students and early career researchers (within 5 yrs of PhD) to cover part of travel and accommodation expenses. Please indicate during registration if you wish to be considered for an IUCr Grant.
Venue
The Recent Advances in Crystallographic Fragment Screening Satellite Workshop will be held at the award-winning National Centre for Synchrotron Science at the Australian Synchrotron in Melbourne, Australia.
Speakers
- Lisa Baker (Vernalis)
- Daren Fearon (XChem, DLS)
- Tobias Krojer (MAX IV)
- Craig Morton (CSIRO)
- Bradley Doak (Monash Institute of Pharmaceutical Sciences)
- May Sharpe (PSI)
- Tatjana Barthel (HZB)
- Alan Riboldi-Tunnicliffe
Sponsorship
Topics & Program
Workshop topics will include
- Fragment screening method development at both synchrotrons and laboratory-based screening facilities
- Application results presented by eminent scientists in the field will be accompanied by computer-based demonstrations in order to familiarize the audience the growing arsenal of new methods.
- Ability for students to present their results/issues to the workshop
Current Schedule (DOCX, 17.83 KB) (downloadable)
Program
08:15 | Bus leaves from Melbourne Convention Center |
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09:00 | Arrival at Australian Synchrotron and registration |
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09:30 – 10:00 | Morning tea/coffee (provided) |
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10:00 – 10:10 | Welcome and opening. Acknowledgement of Country |
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10:10 – 10:40 | The HZB Fragment screening facility – Tatjana Barthel (HZB) |
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10:40 – 11:10 | The FragMAX facility structure-based drug discovery at MAX IV Laboratory - Tobias Krojer (Max IV) |
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11:10 – 11:40 | High-throughput crystallographic and biophysical analysis of crude reaction mixtures for the rapid evolution of fragment hits to early lead-optimisation ready series - Lisa Baker (Vernalis) |
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11:40 – 12:10 | Early career researchers flash presentations: Holger Von Moeller, Lani Davies, Dennis Stegmann |
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12:10 – 13:15 | Lunch (provided) and networking session |
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13:15 – 13:45 | Accelerating structure-enabled drug discovery with high-throughput crystallographic fragment screening - Daren Fearon (DLS) |
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13:45 – 14:15 | Fragment Screening at the Swiss Light Source - May Sharpe (PSI) |
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14:15 – 14:45 | Early career researchers flash presentations: Elzbieta Wator, Roman Hillig |
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14:45 – 15:15 | Fragment Screening at CSIRO - where next? - Craig Morton (CSIRO) |
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15:15 – 15:40 | Afternoon tea/coffee (provided) |
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15:40 – 16:10 | Bradley Doak (Monash University Fragment Platform) |
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16:10 – 16:30 | Developing a Fragment Screening Platform at the Australian Synchrotron - Rachel Williamson & Alan Riboldi-Tunnicliffe (ANSTO Australian Synchrotron) |
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16:30 - 17:00 | Final discussion |
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17:00 – 18:00 | Visiting the MX beamlines |
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18:00 – 20:30 | Mixer (Two Rupees Brewing Company, 1/69 Renver Rd, Clayton) |
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20:45 | Bus leaves for Melbourne Convention Center |
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Applied Research special collection: Crystallographic Fragment Screening
The journal Applied Research is currently aiming to collect a set of peer-reviewed contributions
on the wider topic of crystallographic fragment screening.
We will be starting this collection with a number of invited contributions of speakers at the
IUCR-2023 satellite workshop: “Recent Advances in Crystallographic Fragment Screening.
Authors are invited to contribute mini-reviews, research articles, application notes, short communications and tutorials.
Please click HERE for more information.
Organizing Committee
- Manfred S. Weiss
- Uwe Mueller
- Alan Riboldi-Tunnicliffe
- Rachel Williamson
- Martin Scanlon
- Peter Czabotar
- Stephanie Gras
For more information
