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Supply schedule updates from our Health products customer service team

Delivery schedule

 

Important adjustment to OPAL shutdown schedule 

26 June 2024

ANSTO is now 15 weeks into the most significant maintenance and upgrade program in OPAL’s 17 year history. Last month we communicated a target reactor return to power in early August. Below, please find a further update. 

 

Shutdown schedule 

In preparing for this extremely technical project, ANSTO built a full-size reactor mock-up that allowed our teams to develop, refine, train and practice the required complex processes. However, in the real-world, unique live reactor environment, we have found several novel procedures have taken longer than originally anticipated. 

Based on the data ANSTO now has, and with safety continuing to drive every decision, OPAL is scheduled to return to power the week commencing 18 August 2024. 

 

Nuclear medicine supply 

To date, 96% of imported nuclear medicine products have been supplied to ANSTO in full and on time during the long shutdown period.  

 

We continue to work closely with our international suppliers and logistics providers around the world, to ensure continuity of Mo-99/Tc-99m, Lu-177 and I-131 during the entire shutdown period, subject to these supplier's product availability and logistics. 

 

This extension in the shutdown period will delay the resumption of Chromium supply. ANSTO is reevaluating when Chromium supply will resume, with further updates to be provided. We apologise for any inconveniences caused. 

 

ANSTO will continue to send you regular updates as the project continues and major milestones are reached. If you have any questions, please reach out to our team via health@ansto.gov.au  
 

Tc-99m Gentech delivery update

24 June 2024

Last week ANSTO notified you of Tc-99m Gentech generators supply issues due to a failure of the autoclave.

Over the weekend, ANSTO replaced the failed autoclave and completed the first generator run. Following successful QC testing on Sunday of those generators, we can advise that most customers who missed activity on Friday, and some customers due for delivery on Monday, will receive their generators on Monday 24 June.  All back orders are expected to be cleared by Friday 28 June.

On Sunday, our customer supply chain team contacted impacted customers and will continue today to update customers directly.

ANSTO apologises for the disruption this has caused our customers and their patients.
If you have any questions please contact us via health@ansto.gov.au

Tc-99m Gentech delivery update

20 June 2024

Supply of Tc-99m Gentech generators will be disrupted from June 20 until further notice due to a failure of the autoclave used to terminally sterilise the Tc-99m columns before assembly.

As part of the recent nuclear medicine manufacturing facility (B23) maintenance program, a new autoclave was installed, extensively tested and commissioned. Our facility returned to full operation in early June with the new autoclave successfully operating for the past two weeks.

ANSTO has already begun work to reduce radioactivity within the hotcell to enable safe access for the replacement of the failed autoclave. These efforts will continue through the weekend.

Our team is also working closely with our international suppliers and logistics providers to secure supply where possible on short notice. We will be directly contacting customers impacted by this disruption. Further updates will be shared next Monday.

We apologise for the disruption this causes our customers and their patients. If you have any questions, please contact us via health@ansto.gov.au

ANSTO product supply update

28 May 2024

The planned maintenance at our Nuclear Medicine Processing and Distribution Facility is progressing as planned and is approaching completion. We anticipate resuming operations in early June 2024.

Here’s a reminder of the expected supply resumption dates for some of our ANSTO products:

If you have any further questions, please reach out to our team via health@ansto.gov.au

ProductPlanned supply recommencement of ANSTO product
Gentech Generators

Supply of Gentech Generators to begin transition commencing 03 June 2024.

Full supply is planned to resume week commencing 10 June 2024.

I-131 therapy capsules

Large capsules available for delivery Wednesday 19 June 2024.

Small capsules available for delivery from Thursday 20 June 2024. 

I-131 solutionSolutions available for delivery from Thursday 20 June 2024.

OPAL shutdown schedule update

17 May 2024

ANSTO’s multi-purpose reactor OPAL was shut down in March as part of an essential maintenance and upgrade program. Below, please find the latest update.
 
Shutdown schedule
This planned shutdown is the most significant maintenance and upgrade program in OPAL’s history.  These activities include replacement of the First Reactor Protection System (FRPS) and replacement of the Cold Neutron Source (CNS).
 
To prepare for this first-of-a-kind program, ANSTO built a full-size reactor mock-up that allowed our teams to practice and refine the required procedures over a two-year period. However, in the real-time delivery and unique live reactor environment, we have found several of the process steps have taken longer than anticipated.
 
With safety driving every decision we make, based on the data we have now, the shutdown timeline has been adjusted. We are currently planning to conclude the shutdown activities in late July and return OPAL to power in early August, allowing our teams to maintain the pre-determined August reactor schedule.

Nuclear medicine supply
ANSTO has experienced minor supply disruptions to date and is pleased to report that 90.2% of nuclear medicine products are being supplied to ANSTO in full and on time.
 
We are in continual contact with our international suppliers and logistics providers to ensure we maintain a reliable supply of Mo-99/Tc-99m, Lu-177 and I-131 during this planned long shutdown, subject to these supplier's product availability and logistics.
 
This extension in the shutdown period will now delay the resumption of supply of Chromium until September 2024. We apologise for any inconvenience caused and will continue to provide regular updates to you.
 
Project milestones and achievements
A number of project milestones have now been achieved including the successful CNS removal from the reactor pool, one of the most important milestones of the program, and the commissioning of OPAL’s FRPS.
 
The planned simultaneous maintenance at our Nuclear Medicine Processing and Distribution Facility remains on schedule with the facility due to be back in operation early June 2024.
 
We will continue to send you regular updates. If you have any questions, please feel free to reach out to our team via health@ansto.gov.au

I-131 Capsules

16 May 2024

Our international partner for I-131 has resumed supply and I-131 Therapy Capsules will be
available for delivery week commencing 27 May 2024.
 
Customers are requested to place orders for that week by 1pm Wednesday 22 May 2024,
for delivery from Wednesday 29 May 2024.

Please feel free to contact us if you have any questions via health@ansto.gov.au

I-131 Capsules

13 March 2024

ANSTO has now completed investigation into the identified appearance defect observed in a small number of Sodium (I-131) 50-6000MBq Therapy Capsules, which we advised Customers of on 5 June 2023. 

Following our review, ANSTO has obtained TGA approval and implemented supplementary strengthening into the capsule gelatine casing.

From 18 March 2024, all I-131 Therapy Capsules will include the supplementary strengthening and will again be available to order in the following sizings. 

•    Small capsules 50-600MBq at calibration
•    Large capsules 700-6000MBq at calibration

Please reach out to our team via health@ansto.gov.au if you have any further questions.

Delivery and calibration

I-123 radiochemical

Order cut-off time remains 5 pm on Wednesday the week prior to the shipment unless otherwise specified. 

Available for delivery and calibration on the following dates:

  • 02 July 2024
  • 17 July 2024 - Wednesday
  • 30 July 2024
  • 14 August 2024 - Wednesday
  • 27 August 2024
  • 10 September 2024 
  • 25 September 2024 - Wednesday
  • 08 October 2024
  • 22 October 2024
  • 06 November 2024
  • 19 November 2024
  • 03 December 2024
  • 17 December 2024
I-123 MIBG

Order cut-off time 5 pm on Thursday the week prior to the shipment unless otherwise specified.

Deliveries will take place on the following Thursdays:

  • 27 June 2024
  • 11 July 2024
  • 25 July 2024
  • 08 August 2024
  • 22 August 2024
  • 05 September 2024
  • 19 September 2024
  • 03 October 2024
  • 17 October 2024
  • 31 October 2024
  • 14 November 2024
  • 28 November 2024
  • 12 December 2024
  • 19 December 2024

We will endeavour to keep all hospitals updated as soon we have any further information. We still face some domestic challenges surrounding flights and will continue to be in contact with you regarding the final delivery time to your hospital.   

Get in touch

If you would like to place a product order or have any further questions please contact the Health team.